2,743
edits
Embryology in the Quran: Difference between revisions
→The Formation of Bone and Clothing with Flesh: Better structure, and cleanup of sources and refined arguments.
| [checked revision] | [checked revision] |
Lightyears (talk | contribs) (→The Qur'anic Embryology Verses: Lexicon link for clothed) |
Lightyears (talk | contribs) (→The Formation of Bone and Clothing with Flesh: Better structure, and cleanup of sources and refined arguments.) |
||
| Line 160: | Line 160: | ||
As was alluded to above, there is an argument put forth by those who push this polemic that the "bones" are actually a reference to cartilaginous models that will later ossify. Of course, the text has izhaam, which only means bone - there is no reference to cartilage (Arabic: ghudhroof), so we see that the champions of this deceptive polemic are importing things. Furthermore, as was noted in the previous paragraph, the text has a past tense conjugation followed by the word "then" (fa), thus the logic of the text is that the bones were completed, finished, and then they were clothed with flesh. This does not square with the actual process that some wish to correlate the text with, where cartilaginous skeletal models ossify while muscle forms around them simultaneously.}} | As was alluded to above, there is an argument put forth by those who push this polemic that the "bones" are actually a reference to cartilaginous models that will later ossify. Of course, the text has izhaam, which only means bone - there is no reference to cartilage (Arabic: ghudhroof), so we see that the champions of this deceptive polemic are importing things. Furthermore, as was noted in the previous paragraph, the text has a past tense conjugation followed by the word "then" (fa), thus the logic of the text is that the bones were completed, finished, and then they were clothed with flesh. This does not square with the actual process that some wish to correlate the text with, where cartilaginous skeletal models ossify while muscle forms around them simultaneously.}} | ||
====Bone and Muscle Formation According to Medical Science==== | |||
In order to compare with science the Qur'anic statement that Allah makes 'ithaman (bones<ref name="LLitham"></ref>) and then clothes (fa-kasawna<ref name="LLkasawa"></ref>) the bones with lahman (flesh<ref name="LLlahm"></ref>), first we should see what science has discovered about the process of bone and muscle formation. Here is a brief description for both of them, without any detail on the relative timing of parallel processes. The section that follows afterwards contains numerous cited scientific sources stating the timing of these processes. | |||
Mesoderm is the middle of the three layers of the early embryo. Some of the mesoderm cells form blocks called somites either side of the neural tube (this tube will eventually form the spinal cord and brain). These somites will differentiate to form the cartilage models and connective tissues (including muscles) of the axial skeleton (i.e. everything except the limbs and pelvis). | |||
Another area of mesoderm (lateral plate mesoderm) proliferates especially quickly in certain positions to form the limb buds. There, mesenchyme cells condense into distinct masses within the limb buds. These mesenchyme cells differentiate into chondrocytes, which produce cartilage. Cartilage 'models' (or 'templates') of the future bones gradually form. Once the cartilage models have formed and while they are still growing, the cartilage is literally replaced with actual bone by osteoblasts (ossification) working outwards from centres of the cartilage models. Osteoclasts remove the remnants of the mineralized cartilage. Ossification also starts in the axial skeleton some time after it has begun in the limbs, except for the upper and lower jaw, which starts to ossify slightly earlier. | |||
Meanwhile, the process of muscle formation begins as soon as the limb buds appear. Myoblast cells migrate from somites to the limb buds. They aggregate into distinct masses, differentiating and fusing into muscle fibres, as the condensing mesenchyme starts to chondrify, and before the resulting cartilage models begin to ossify. | |||
====The Timing of These Processes==== | |||
Here is the scientific evidence for the contemporaneous development of cartilage/bone and muscles: | Here is the scientific evidence for the contemporaneous development of cartilage/bone and muscles: | ||
A very detailed account of musculo-skeletal development in the human limb by clinical-geneticist Robert Jan Galjaard can be read online.<ref>Galjaard, R.J.H 2003. [http://repub.eur.nl/res/pub/10474/030924_Galjaard,%20Robert-Jan%20Harmen.pdf Mapping Studies of Congenital Limb Anomalies]. Page 16</ref><ref> This diagram (strictly speaking for mice, but considered a good analog for humans in this respect) also helps us appreciate the complexity of the process: | |||
[http://php.med.unsw.edu.au/embryology/index.php?title=Musculoskeletal_System_-_Muscle_Development#Mouse_Limb_Muscle Musculoskeletal System - Muscle Development]</ref>It details that muscle precursor cells migrate from the somites into the limb buds (ca. day 26), well before the condensing core of mesenchyme has started to chondrify into cartilage bone models in the upper part of the upper limb (ca. day 37), followed by the lower part (ca. day 41). The myoblasts have grouped into distinct masses by this stage and are differentiating into muscle fibres. The upper limbs later start to ossify (ca. day 54). | |||
Professor Peter Law confirms that myoblasts are found in the limb buds day 26.<ref>Law, Peter et al., Pioneering Human Myoblast Genome Therapy as a Platform Technology of Regenerative Medicine. In: Stem Cell Therapy. Erik Greer (Editor). Nova Science Publishers, Inc. 2006. Page 3.</ref> | |||
Myoblasts have aggregated into ventral and dorsal masses in the upper limb by day 36 and the start of chondrification.<ref>Sivakumar, B. ''Congenital Hand Differences'' in Farhadieh, R. et. al. (ed.) Plastic and Reconstructive Surgery: Approaches and Techniques, Wiley, p.660</ref> | |||
According to Rugh, Building blocks are present for 40 pairs of muscles, which are located from the base of the skull to the bottom of the spinal column by day 28<ref>Conception to Birth Roberts Rugh, Ph.D., Landrum B. Shettles, Ph.D., M.D. Harper & Row, (New York), 1971, p.35</ref>. Muscles appear in the pelvis day 31<ref>ibid. p.43</ref>. Movement of the muscles is being controlled by the nervous system by the 6th week <ref>ibid. p.34</ref>. All of the muscle blocks have appeared by day 36 after conception<ref>ibid. p.46</ref>. | |||
In the 10th edition (2016) of the Developing Human, Keith Moore says that ossification of the long bones begins in the 8th week, starting with the upper limbs, followed by the lower limbs and pelvis<ref>Keith L. Moore, Ph..D., FIAC, FRSM T.V.N. Persaud, M.D., Ph.D., D.Sc., FRCPath W.B., The Developing Human: Clinically Oriented Embryology, , 10th Edition, Elseiver (Philadelphia), 2016, p. p.349</ref> (which concurs with Galjaard cited above). | |||
The | |||
It is apparent from the above that muscle masses have started to form around the mesenchyme condensations around the same time as they begin to chondrify into cartilage models of the limb bones, and long before they have even begun to ossify. The further development of the muscles and cartilage and bones then continue in parallel. | |||
====Problems With The Qur'anic Description==== | |||
Firstly, proponents of Qur'anic embryology have to explain why the author of the Qur'an was incorrect in their description and mentioned not cartilage (ghudhroof)<ref name="LLghudtroof">غضروف ghudhroof, alternatively spelt غرضوف ghurdoof - [http://www.studyquran.org/LaneLexicon/Volume6/00000032.pdf Lane's Lexicon] Volume 6, page 2248</ref>) but only bone ('itham)<ref name="LLitham"></ref>, which starts to form well after muscles. | |||
Secondly, muscle and bone (or their precursors) develop contemporaneously, although the parallel processes start when muscle begins developing around condensations of mesenchyme that have only just begun to diffentiate into cartilage. Therefore, there is no scientific basis for the Qur'anic claim of a stage in which bone is later covered with flesh after its own formation. The prefix fa before khalaqna means "and then", indicating an uninterrupted sequence.<ref>فَ fa - [http://www.studyquran.org/LaneLexicon/Volume6/00000105.pdf Lane's Lexicon] Volume 6, page 2322</ref> | |||
Even if we were to accept that the Qur'an was only referring to precursors of bone and not bone itself, even though it used the Arabic word for bone ('itham), and not cartilage (ghurdoof), the embryology is still wrong. Even if, with further and unjustifiable generosity, we suppose that the Qur'an means only the very beginning of the formation of the cartilage (chondrification) before they are in any sense complete shapes and the beginning of the formation of muscles, even this happens at the same stage (around day 41). Going back earlier still, it can even be pointed out that the precursors of muscles (myoblasts) and cartilage (mesenchyme) are present in the limb bud as soon as it arises. Of course, the natural reading of verse 23:14 is that the bones have some sort of meaningful shape, and can meaningfully be called bones. This is certainly not the case when the condensed mesenchyme starts to chondrify. | |||
We have more evidence that 23:14 refers to things already recognisable as bones being clothed with muscles or flesh elsewhere in the Qur'an. Verse 2:259 uses the same Arabic words as does 23:14 for 'bones', 'clothed' and 'flesh' to describe the resurrection of a donkey which had been dead for 100 years. The main embryology passages, such as verse 22:5 (see quote above) suggests that embryological development has similarities with resurrection. | |||
{{Quote|{{Qtt|2|259}}|''' | {{Quote|{{Qtt|2|259}}|'''Pickthall:''' ...and look at your ass; and that We may make you a sign to men, and look at the bones, how We set them together, then clothed them with flesh... | ||
<BR>'''Transliteration:''' ''waonthur ila himarika walinajAAalaka ayatan lilnnasi waonthur ila alAAithami kayfa nunshizuha thumma naksooha lahman''}} | <BR>'''Transliteration:''' ''waonthur ila himarika walinajAAalaka ayatan lilnnasi waonthur ila alAAithami kayfa nunshizuha thumma naksooha lahman''}} | ||
The resurrected donkey's bones clearly had no flesh on them (were unclothed), and then Allah clothed them. This rather suggests that when the same words are used in 23:14 to describe the developing | The resurrected donkey's bones clearly had no flesh on them (were unclothed), and then Allah clothed them. This rather suggests that when the same words are used in 23:14 to describe the developing embryo, the author had in mind a small skeleton without any muscles (possibly within some remnant of the mudghah stage), which is then clothed with muscles or flesh. | ||
===The Beginning of the Fetal Stage=== | ===The Beginning of the Fetal Stage=== | ||