Embryology in the Quran: Difference between revisions

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{{Quote-text|{{cite web|url= http://poetsgate.com/poem_14021.html|title= الحمد لله لا شريك له|publisher= PoetsGate (Arabic)|author= |date= February 15, 2007|archiveurl= http://archive.is/6XW6e|deadurl=no}}|الخـالق البـارئ المصـور في الأرحام ماء حتى يصير دما
{{Quote-text|{{cite web|url= http://poetsgate.com/poem_14021.html|title= الحمد لله لا شريك له|publisher= PoetsGate (Arabic)|author= |date= February 15, 2007|archiveurl= http://archive.is/6XW6e|deadurl=no}}|الخـالق البـارئ المصـور في الأرحام ماء حتى يصير دما
<br>Translation: The creator, the maker, the fashioner, in the wombs water until it becomes blood}}
<br>Translation: The creator, the maker, the fashioner, in the wombs water until it becomes blood}}
Water (maa') is used here as a euphemism for semen, just as we sometimes find in the Quran and hadiths (see above).</ref>
Water (maa') is used here as a euphemism for semen, just as we sometimes find in the Quran and hadiths (see above).</ref> From the perspective of seeing the Qur'an as a divine text illuminating the knowledge of mankind, the usage of the 'alaqah must be seen as a failure to "clearly" convey the actual knowledge the author allegedly possessed.  
 
It would be most unwise for the author of the Quran to use a word that has a specific, widely understood biological meaning to describe a biological process (embryology) if that meaning was not the intention. For the same reason it would be foolish even to use clotted blood merely as a visual metaphor. A perfect author would avoid arousing any such suspicion of inaccurate biology with his choice of words.


===='Alaqah in pre-Islamic poetry====
===='Alaqah in pre-Islamic poetry====
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#Somites (bilateral rows of blocks of cells that will migrate and develop into segments of the body) are protrusions, but teeth marks are indentations.
#Somites (bilateral rows of blocks of cells that will migrate and develop into segments of the body) are protrusions, but teeth marks are indentations.


Verse 22:5<ref name="22-5">O People, if you should be in doubt about the Resurrection, then [consider that] indeed, We created you from dust, then from a sperm-drop, then from a clinging clot, and then from a lump of flesh, formed and unformed - that We may show you. And We settle in the wombs whom We will for a specified term, then We bring you out as a child, and then [We develop you] that you may reach your [time of] maturity. And among you is he who is taken in [early] death, and among you is he who is returned to the most decrepit [old] age so that he knows, after [once having] knowledge, nothing. And you see the earth barren, but when We send down upon it rain, it quivers and swells and grows [something] of every beautiful kind<br>{{Quran|22|5}}</ref> mentions that the mudghah is formed and without form. Given that this stage appears before the 'itham (bones) stage, such a 'clarification' gives no additional information whatsoever. Such vagueness of description is typical of an author who is merely pretending to have true knowledge.
Verse 22:5<ref name="22-5">O People, if you should be in doubt about the Resurrection, then [consider that] indeed, We created you from dust, then from a sperm-drop, then from a clinging clot, and then from a lump of flesh, formed and unformed - that We may show you. And We settle in the wombs whom We will for a specified term, then We bring you out as a child, and then [We develop you] that you may reach your [time of] maturity. And among you is he who is taken in [early] death, and among you is he who is returned to the most decrepit [old] age so that he knows, after [once having] knowledge, nothing. And you see the earth barren, but when We send down upon it rain, it quivers and swells and grows [something] of every beautiful kind<br>{{Quran|22|5}}</ref> mentions that the mudghah is formed and without form. Given that this stage appears before the 'itham (bones) stage, such a 'clarification' gives no additional information whatsoever. Such vagueness of description is typical of premodern understanding of biology and embryology.  


===The Bones and Clothing with Flesh Stages===
===The Bones and Clothing with Flesh Stages===
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====The Timing of These Processes====
====The Timing of These Processes====


Here is the scientific evidence for the contemporaneous development of cartilage/bone and muscles.  
The scientific evidence shows that the development of cartilage/bone and muscles is contemporaneous.  


A very detailed account of musculo-skeletal development in the human limb by clinical-geneticist Robert Jan Galjaard can be read online.<ref>Galjaard, R.J.H. [http://repub.eur.nl/res/pub/10474/030924_Galjaard,%20Robert-Jan%20Harmen.pdf Mapping Studies of Congenital Limb Anomalies]. Ablasserdam: Haveka, B.V., 2003, page 16 [http://www.webcitation.org/6lFwBQq9z webcitation archive link]</ref> It details that muscle precursor cells migrate from the somites into the limb buds (ca. day 26), well before the condensing core of mesenchyme has started to chondrify into cartilage bone models in the upper part of the upper limb (ca. day 37), followed by the lower part (ca. day 41). The myoblasts have grouped into distinct masses by this stage and are differentiating into muscle fibres. The upper limbs later start to ossify (ca. day 54). Chondrification of mesenchyme, the grouping of myogenic masses, and ossification all occur in a proximal-distal order (upper to lower part of each limb). The digits of the hands only start to chondrify ca. day 51.
A very detailed account of musculo-skeletal development in the human limb by clinical-geneticist Robert Jan Galjaard covers this subject.<ref>Galjaard, R.J.H. [http://repub.eur.nl/res/pub/10474/030924_Galjaard,%20Robert-Jan%20Harmen.pdf Mapping Studies of Congenital Limb Anomalies]. Ablasserdam: Haveka, B.V., 2003, page 16 [http://www.webcitation.org/6lFwBQq9z webcitation archive link]</ref> It details that muscle precursor cells migrate from the somites into the limb buds (ca. day 26), well before the condensing core of mesenchyme has started to chondrify into cartilage bone models in the upper part of the upper limb (ca. day 37), followed by the lower part (ca. day 41). The myoblasts have grouped into distinct masses by this stage and are differentiating into muscle fibres. The upper limbs later start to ossify (ca. day 54). Chondrification of mesenchyme, the grouping of myogenic masses, and ossification all occur in a proximal-distal order (upper to lower part of each limb). The digits of the hands only start to chondrify ca. day 51.


Professor Peter Law confirms that myoblasts are found in the limb buds day 26.<ref>Law, Peter et al., ''Pioneering Human Myoblast Genome Therapy as a Platform Technology of Regenerative Medicine.'' In: Stem Cell Therapy. Erik Greer (Editor). Nova Science Publishers, Inc. 2006. Page 3.</ref>
Professor Peter Law confirms that myoblasts are found in the limb buds day 26.<ref>Law, Peter et al., ''Pioneering Human Myoblast Genome Therapy as a Platform Technology of Regenerative Medicine.'' In: Stem Cell Therapy. Erik Greer (Editor). Nova Science Publishers, Inc. 2006. Page 3.</ref>
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Firstly, it is clear that bone formation (ossification) begins long after muscle has begun to develop around its precursors. Therefore, there is no scientific basis for the Quranic claim of a stage in which bone is later covered with flesh after its own formation. The prefix fa before kasawna means "and then", indicating an uninterrupted sequence.<ref>فَ fa - [http://www.studyquran.org/LaneLexicon/Volume6/00000105.pdf Lane's Lexicon] Volume 6, page 2322</ref>
Firstly, it is clear that bone formation (ossification) begins long after muscle has begun to develop around its precursors. Therefore, there is no scientific basis for the Quranic claim of a stage in which bone is later covered with flesh after its own formation. The prefix fa before kasawna means "and then", indicating an uninterrupted sequence.<ref>فَ fa - [http://www.studyquran.org/LaneLexicon/Volume6/00000105.pdf Lane's Lexicon] Volume 6, page 2322</ref>


Next, if proponents of Quranic embryology suppose that the Quran was only referring to precursor cartilage models of the bones and not bone itself, they have to explain why the author of the Quran mentioned not cartilage (ghudhroof)<ref name="LLghudtroof">غضروف ghudhroof, alternatively spelt غرضوف ghurdoof - [http://www.studyquran.org/LaneLexicon/Volume6/00000032.pdf Lane's Lexicon] Volume 6, page 2248</ref>) but only bone ('itham)<ref name="LLitham"></ref>, which starts to form well after muscles.
Next, if proponents of unerring Quranic embryology suppose that the Quran was only referring to precursor cartilage models of the bones and not bone itself, they have to explain why the author of the Quran mentioned not cartilage (ghudhroof)<ref name="LLghudtroof">غضروف ghudhroof, alternatively spelt غرضوف ghurdoof - [http://www.studyquran.org/LaneLexicon/Volume6/00000032.pdf Lane's Lexicon] Volume 6, page 2248</ref>) but only bone ('itham)<ref name="LLitham"></ref>, which starts to form well after muscles.


In any case its embryology would still be wrong. We have seen that muscle and bone (or their precursors) develop contemporaneously, although the parallel processes start when muscle begins developing around condensations of mesenchyme that have only just begun to differentiate into cartilage, as detailed above.  
In any case its embryology would still be wrong. We have seen that muscle and bone (or their precursors) develop contemporaneously, although the parallel processes start when muscle begins developing around condensations of mesenchyme that have only just begun to differentiate into cartilage, as detailed above.  
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Of course, the natural reading of verse 23:14 is that the bones have some sort of meaningful shape, and can meaningfully be called bones. This is certainly not the case when the condensed mesenchyme has merely started to produce cartilage. Furthermore, the natural reading of verse 23:14 is that all the bones have some meaningful presence worthy of the label 'bones' before Allah clothes them with flesh. As noted in the evidence above, fingers only start to even chondrify after muscle formation is already well underway in the upper part of the limbs.
Of course, the natural reading of verse 23:14 is that the bones have some sort of meaningful shape, and can meaningfully be called bones. This is certainly not the case when the condensed mesenchyme has merely started to produce cartilage. Furthermore, the natural reading of verse 23:14 is that all the bones have some meaningful presence worthy of the label 'bones' before Allah clothes them with flesh. As noted in the evidence above, fingers only start to even chondrify after muscle formation is already well underway in the upper part of the limbs.


We have more evidence that 23:14 refers to things already recognisable as bones being clothed with muscles or flesh elsewhere in the Quran. Verse 2:259 uses the same Arabic words as does 23:14 for 'bones', 'clothed' and 'flesh' to describe the resurrection of a donkey which had been dead for 100 years.<ref>[...]and look at your ass; and that We may make you a sign to men, and look at the bones, how We set them together, then clothed them with flesh[...]
We have more evidence that 23:14 refers to things already recognizable as bones being clothed with muscles or flesh elsewhere in the Quran. Verse 2:259 uses the same Arabic words as does 23:14 for 'bones', 'clothed' and 'flesh' to describe the resurrection of a donkey which had been dead for 100 years.<ref>[...]and look at your ass; and that We may make you a sign to men, and look at the bones, how We set them together, then clothed them with flesh[...]
<BR>Transliteration: ''waonthur ila himarika walinajAAalaka ayatan lilnnasi waonthur ila alAAithami kayfa nunshizuha thumma naksooha lahman''<nowiki>}}</nowiki><br>{{Quran|2|259}}</ref> The main embryology passages such as verse 22:5 suggest that embryological development has similarities with resurrection.<ref name="22-5" />
<BR>Transliteration: ''waonthur ila himarika walinajAAalaka ayatan lilnnasi waonthur ila alAAithami kayfa nunshizuha thumma naksooha lahman''<nowiki>}}</nowiki><br>{{Quran|2|259}}</ref> The main embryology passages such as verse 22:5 suggest that embryological development has similarities with resurrection.<ref name="22-5" />


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{{Quote|{{Quran-range|53|45|46}}|And that He createth the two spouses, the male and the female [alzzawjayni alththakara waalontha ٱلزَّوْجَيْنِ ٱلذَّكَرَ وَٱلْأُنثَىٰ], From a drop (of seed) when it is poured forth [nutfatin itha tumna نُّطْفَةٍ إِذَا تُمْنَىٰ];}}
{{Quote|{{Quran-range|53|45|46}}|And that He createth the two spouses, the male and the female [alzzawjayni alththakara waalontha ٱلزَّوْجَيْنِ ٱلذَّكَرَ وَٱلْأُنثَىٰ], From a drop (of seed) when it is poured forth [nutfatin itha tumna نُّطْفَةٍ إِذَا تُمْنَىٰ];}}


However, verses 75:37-39 use the same language about gender, but after the 'alaqah stage. 75:39 uses the exact same phrase as in 53:45, "alzzawjayni alththakara waalontha" ("of the two spouses, the male and the female"}, which is also similar to the word used in 35:11, azwajan (male / female pair).  
However, verses 75:37-39 use the same language about gender, but after the 'alaqah stage. 75:39 uses the exact same phrase as in 53:45, "وَأَنَّهُۥ خَلَقَ ٱلزَّوْجَيْنِ ٱلذَّكَرَ وَٱلْأُنثَىٰ" "wa innahu khalaqa alzzawjayni aldhdhakara waaluntha" ("verily he created the two spouses, the male and the female"}, which is also similar to the word used in 35:11, azwajan (male / female pair).  


{{Quote|{{Quran-range|75|37|39}}|Was he not a drop [nutfatan نُطْفَةً] of fluid [manayin مَّنِىٍّ] which gushed forth [yumna يُمْنَىٰ]? Then he became a clot [alaqatan عَلَقَةً]; then (Allah) shaped and fashioned And made of him a pair, the male and female [alzzawjayni alththakara waalontha ٱلزَّوْجَيْنِ ٱلذَّكَرَ وَٱلْأُنثَىٰ].}}
{{Quote|{{Quran-range|75|37|39}}|Was he not a drop [nutfatan نُطْفَةً] of fluid [manayin مَّنِىٍّ] which gushed forth [yumna يُمْنَىٰ]? Then he became a clot [alaqatan عَلَقَةً]; then (Allah) shaped and fashioned And made of him a pair, the male and female [alzzawjayni alththakara waalontha ٱلزَّوْجَيْنِ ٱلذَّكَرَ وَٱلْأُنثَىٰ].}}


Apologists interpret 75:39 to mean that the external genitalia and gonads are formed after the 'alaqah stage, knowing that the gender of the child has already been determined genetically at the moment of conception as stated above. To be consistent, they would have to accept that 35:11 and 53:45-46 are merely saying that babies, male and female, start off as a nutfah (drop of semen).  
Apologists interpret 75:39 to mean that the external genitalia and gonads are formed after the 'alaqah stage, knowing that the gender of the child has already been determined genetically at the moment of conception as stated above. The point from 35:11 and 53:45-46 seems to be rather .  


Moreover, if 53:45 is taken literally as indicating 'when' gender is determined, it would be inaccurate, because millions of sperm are emitted, some with an x chromosome, some with a y chromosome. Gender is determined not when the semen is emitted, but when the egg is fertilized by one of the sperm cells, which can take anything from half an hour to 12 hours for the first of them to reach the egg, and then more time for one of the many that arrive to successfully penetrate it.
Moreover, if 53:45 is taken literally as indicating 'when' gender is determined, it would be inaccurate, because millions of sperm are emitted, some with an x chromosome, some with a y chromosome. Gender is determined not when the semen is emitted, but when the egg is fertilized by one of the sperm cells, which can take anything from half an hour to 12 hours for the first of them to reach the egg, and then more time for one of the many that arrive to successfully penetrate it.
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*Other genetic configurations include XXX, and XXY (1 in 1000 people)<ref>{{cite web|url=http://www.isna.org/faq/frequency |title=How common is intersex? &#124; Intersex Society of North America |publisher=Isna.org |accessdate=10 October 2016}}</ref>. These people have no discrepancy between their gonads and external genitalia, but there may be problems with sex hormone levels, and overall sexual development.
*Other genetic configurations include XXX, and XXY (1 in 1000 people)<ref>{{cite web|url=http://www.isna.org/faq/frequency |title=How common is intersex? &#124; Intersex Society of North America |publisher=Isna.org |accessdate=10 October 2016}}</ref>. These people have no discrepancy between their gonads and external genitalia, but there may be problems with sex hormone levels, and overall sexual development.


According to Leonard Sax, when the term intersex is "restricted to those conditions in which chromosomal sex is inconsistent with phenotypic sex, or in which the phenotype is not classifiable as either male or female", around 0.018% of the population are intersex. This definition excludes Klinefelter syndrome and many other variations.<ref>Sax, L., ''How common is intersex? a response to Anne Fausto-Sterling'' Journal of Sex Research, volume 39, issue 3, pp.174–178 (2002) doi 10.1080/00224490209552139 pmid 12476264</ref>
According to Leonard Sax, when the term intersex is "restricted to those conditions in which chromosomal sex is inconsistent with phenotypic sex, or in which the phenotype is not classifiable as either male or female", around 0.018% of the population are intersex. This definition excludes Klinefelter syndrome and many other variations.<ref>Sax, L., ''How common is intersex? a response to Anne Fausto-Sterling'' Journal of Sex Research, volume 39, issue 3, pp.174–178 (2002) doi 10.1080/00224490209552139 pmid 12476264</ref> There is no mention of these conditions in any conceivable interpretation of the Qur'an.


====Sperm within Semen====
====Sperm within Semen====
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{{Quran|76|2}} states that "Verily We created Man from a drop of mingled sperm [nutfatin amshajin نُّطْفَةٍ أَمْشَاجٍ], in order to try him: So We gave him (the gifts), of Hearing and Sight." Some claim that this is a reference to male semen and follicular fluid. There are two problems with this claim:
{{Quran|76|2}} states that "Verily We created Man from a drop of mingled sperm [nutfatin amshajin نُّطْفَةٍ أَمْشَاجٍ], in order to try him: So We gave him (the gifts), of Hearing and Sight." Some claim that this is a reference to male semen and follicular fluid. There are two problems with this claim:


1) By the time a sperm cell reaches a woman's fallopian tube where fertilisation occurs, it is no longer swimming in male semen, but has instead swam through cervical mucus, then binded to epithelium of the uterine tube where it undegoes capacitation and detaches again, then through a combination of muscular movements of the tube and some swimming movements makes its way up the tube.<ref>[https://clinicalgate.com/transport-of-gametes-and-fertilization/ Clinicalgate.com - Transport of gametes and fertilization]</ref>; and  
1) By the time a sperm cell reaches a woman's fallopian tube where fertilisation occurs, it is no longer swimming in male semen, but has instead swam through cervical mucus, then binded to epithelium of the uterine tube where it undergoes capacitation and detaches again, then through a combination of muscular movements of the tube and some swimming movements makes its way up the tube.<ref>[https://clinicalgate.com/transport-of-gametes-and-fertilization/ Clinicalgate.com - Transport of gametes and fertilization]</ref>; and  


2) Follicular fluid is part of the developmental environment of the female ovum (oocyte, egg cell) before the egg is released from the egg follicle. While some fluid is released at the same time into the fallopian tube, the ovum is pushed along the fallopian tube by fallopian cilia (microscopic hairs) and is bathed in another type of tubal fluid secretion.<ref>[https://britannica.com/science/ovulation Britannica.com - Ovulation]</ref>
2) Follicular fluid is part of the developmental environment of the female ovum (oocyte, egg cell) before the egg is released from the egg follicle. While some fluid is released at the same time into the fallopian tube, the ovum is pushed along the fallopian tube by fallopian cilia (microscopic hairs) and is bathed in another type of tubal fluid secretion.<ref>[https://britannica.com/science/ovulation Britannica.com - Ovulation]</ref>


For these reasons, fertilisation can not reasonably be described as a mingling of semen and follicular fluid. Rather, the Qur'anic statement corresponds with the Galenic theory of two semens, which was widespread in the region and time. [[Sources_of_Islamic_Theories_of_Reproduction|Galen's influence]] is also apparent in numerous hadiths relating to this notion and other issues relating to human reproduction.
For these reasons, fertilization cannot reasonably be described as a mingling of semen and follicular fluid. Rather, the Qur'anic statement corresponds with the Galenic theory of two semens, male and female, which was widespread in the region and time. [[Sources_of_Islamic_Theories_of_Reproduction|Galen's influence]] is also apparent in numerous hadiths relating to this notion and other issues relating to human reproduction.


====Fetus is in Three Layers of darkness====
====Fetus is in Three Layers of darkness====
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====The Minimum Period of Fetal Viability====
====The Minimum Period of Fetal Viability====
   
   
Another claim is that the Quran correctly states that the minimum period for gestation of a viable baby is 6 months. This claim is based on two Quranic verses, the first of which states that a child is weaned for two years (24 lunar months), and the other that the bearing and weaning of a child lasts for 30 lunar months.<ref>And We have enjoined upon man concerning his parents. His mother beareth him in weakness upon weakness, and his weaning is in two years. Give thanks unto Me and unto thy parents. Unto Me is the journeying.<br>{{Quran|31|14}}</ref><ref>And We have commended unto man kindness toward parents. His mother beareth him with reluctance, and bringeth him forth with reluctance, and the bearing of him and the weaning of him is thirty months, till, when he attaineth full strength and reacheth forty years, he saith: My Lord! Arouse me that I may give thanks for the favour wherewith Thou hast favoured me and my parents, and that I may do right acceptable unto Thee. And be gracious unto me In the matter of my seed. Lo! I have turned unto Thee repentant, and lo! I am of those who surrender (unto Thee).<br>{{Quran|46|15}}</ref> Yusuf Ali makes this claim in the notes of his translation for verse 46:15, presumably having noticed that the two verses in combination do not equate to a 9 month pregnancy.
Another claim is that the Qur'an correctly states that the minimum period for gestation of a viable baby is 6 months. This claim is based on two Quranic verses, the first of which states that a child is weaned for two years (24 lunar months), and the other that the bearing and weaning of a child lasts for 30 lunar months.<ref>And We have enjoined upon man concerning his parents. His mother beareth him in weakness upon weakness, and his weaning is in two years. Give thanks unto Me and unto thy parents. Unto Me is the journeying.<br>{{Quran|31|14}}</ref><ref>And We have commended unto man kindness toward parents. His mother beareth him with reluctance, and bringeth him forth with reluctance, and the bearing of him and the weaning of him is thirty months, till, when he attaineth full strength and reacheth forty years, he saith: My Lord! Arouse me that I may give thanks for the favour wherewith Thou hast favoured me and my parents, and that I may do right acceptable unto Thee. And be gracious unto me In the matter of my seed. Lo! I have turned unto Thee repentant, and lo! I am of those who surrender (unto Thee).<br>{{Quran|46|15}}</ref> Yusuf Ali makes this claim in the notes of his translation for verse 46:15, presumably having noticed that the two verses in combination do not equate to a 9 month pregnancy.


Six lunar months equates to 22 weeks. The claim that this is the minimum period for fetal viability is unsupported by modern medical science. It has changed, at least in recent history, and was never 22 weeks or 6 lunar months prior to the era of modern medicine, being likely to have been at least 30 weeks. Now, it has shrunk to only 19 weeks in countries with advanced pediatric medicine.<ref>"A fetus is defined as being viable if it has the ability to 'potentially able to live outside the mother's womb [that is, can survive], albeit with artificial help.' In the fifties viability was reached about 30 weeks after conception. Modern medical technology changed that to 25 weeks in the seventies. Now viability continues to be pushed further and further back in the pregnancy and is now as early as 19 weeks.  
Six lunar months equates to 22 weeks. The claim that this is the minimum period for fetal viability is unsupported by modern medical science. It has changed, at least in recent history, and was never 22 weeks or 6 lunar months prior to the era of modern medicine, being likely to have been at least 30 weeks. Now, it has shrunk to only 19 weeks in countries with advanced pediatric medicine.<ref>"A fetus is defined as being viable if it has the ability to 'potentially able to live outside the mother's womb [that is, can survive], albeit with artificial help.' In the fifties viability was reached about 30 weeks after conception. Modern medical technology changed that to 25 weeks in the seventies. Now viability continues to be pushed further and further back in the pregnancy and is now as early as 19 weeks.  
21 and 22 week premature babies are now supported routinely, and have a good chance of survival. By 24 weeks after conception, premature babies have a 40% chance of reaching adulthood without any major complications. By 28 weeks, the chance is 90%. By 29 weeks, survival is almost definite. (Note: These percentages are from reports written during the late 1980s. Current survival rates are most likely much higher.)"<br>[http://web.archive.org/web/20050205142039/http://www.abortioninfo.net/facts/development4.shtml Fetal Development/Viability] - Abortioninfo</ref> The minimum period of fetal viability in many third-world countries would still be around 30 weeks.
21 and 22 week premature babies are now supported routinely, and have a good chance of survival. By 24 weeks after conception, premature babies have a 40% chance of reaching adulthood without any major complications. By 28 weeks, the chance is 90%. By 29 weeks, survival is almost definite. (Note: These percentages are from reports written during the late 1980s. Current survival rates are most likely much higher.)"<br>[http://web.archive.org/web/20050205142039/http://www.abortioninfo.net/facts/development4.shtml Fetal Development/Viability] - Abortioninfo</ref> The minimum period of fetal viability in many less-developed countries would still be around 30 weeks.


====The End of Cell Differentiation====
====The End of Cell Differentiation====
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